helicos-load: command not found

Have You tried accessing the binary with the full path?

Maybe Your $PATH variable doesn't contain the default paths? echo $PATH should give something like:

[root@server ~]# echo $PATH
/usr/local/sbin:/usr/local/bin:/sbin:/bin:/usr/sbin:/usr/bin:/root/bin

If it's empty, You may set the PATH variable with this command

export PATH="/usr/local/sbin:/usr/local/bin:/sbin:/bin:/usr/sbin:/usr/bin:/root/bin"

On Debian possible default full paths are:

/usr/bin/helicos-load - from package: sra-toolkit

You may install the required package with command apt-get install {package}
Error in other languages:
helicos-load: bevel nie gevind nie
helicos-load: comandă negăsită
helicos-load: comando não encontrado
helicos-load: commande introuvable
helicos-load: command not found
helicos-load: käsku ei ole
helicos-load: không tìm thấy lệnh
helicos-load: komanda nerasta
helicos-load: Kommando nicht gefunden.
helicos-load: kommandot finns inte
helicos-load: komut yok
helicos-load: nie znaleziono polecenia
helicos-load: níor aimsíodh an t-ordú
helicos-load: no se encontró la orden
helicos-load: no s'ha trobat l'ordre
helicos-load: opdracht niet gevonden
helicos-load: parancs nem található
helicos-load: perintah tidak ditemukan
helicos-load: príkaz nenájdený
helicos-load: příkaz nenalezen
helicos-load: команда не найдена
helicos-load: командата не е открита
helicos-load: 命令找不到
helicos-load: コマンドが見つかりません