makeprofiledb: command not found

Have You tried accessing the binary with the full path?

Maybe Your $PATH variable doesn't contain the default paths? echo $PATH should give something like:

[root@server ~]# echo $PATH
/usr/local/sbin:/usr/local/bin:/sbin:/bin:/usr/sbin:/usr/bin:/root/bin

If it's empty, You may set the PATH variable with this command

export PATH="/usr/local/sbin:/usr/local/bin:/sbin:/bin:/usr/sbin:/usr/bin:/root/bin"

On Debian possible default full paths are:

/usr/bin/makeprofiledb - from package: ncbi-blast+

You may install the required package with command apt-get install {package}
Error in other languages:
makeprofiledb: bevel nie gevind nie
makeprofiledb: comandă negăsită
makeprofiledb: comando não encontrado
makeprofiledb: commande introuvable
makeprofiledb: command not found
makeprofiledb: käsku ei ole
makeprofiledb: không tìm thấy lệnh
makeprofiledb: komanda nerasta
makeprofiledb: Kommando nicht gefunden.
makeprofiledb: kommandot finns inte
makeprofiledb: komut yok
makeprofiledb: nie znaleziono polecenia
makeprofiledb: níor aimsíodh an t-ordú
makeprofiledb: no se encontró la orden
makeprofiledb: no s'ha trobat l'ordre
makeprofiledb: opdracht niet gevonden
makeprofiledb: parancs nem található
makeprofiledb: perintah tidak ditemukan
makeprofiledb: príkaz nenájdený
makeprofiledb: příkaz nenalezen
makeprofiledb: команда не найдена
makeprofiledb: командата не е открита
makeprofiledb: 命令找不到
makeprofiledb: コマンドが見つかりません