hmm2calibrate: command not found

Have You tried accessing the binary with the full path?

Maybe Your $PATH variable doesn't contain the default paths? echo $PATH should give something like:

[root@server ~]# echo $PATH
/usr/local/sbin:/usr/local/bin:/sbin:/bin:/usr/sbin:/usr/bin:/root/bin

If it's empty, You may set the PATH variable with this command

export PATH="/usr/local/sbin:/usr/local/bin:/sbin:/bin:/usr/sbin:/usr/bin:/root/bin"

On Debian possible default full paths are:

/usr/bin/hmm2calibrate - from package: hmmer2

You may install the required package with command apt-get install {package}
Error in other languages:
hmm2calibrate: bevel nie gevind nie
hmm2calibrate: comandă negăsită
hmm2calibrate: comando não encontrado
hmm2calibrate: commande introuvable
hmm2calibrate: command not found
hmm2calibrate: käsku ei ole
hmm2calibrate: không tìm thấy lệnh
hmm2calibrate: komanda nerasta
hmm2calibrate: Kommando nicht gefunden.
hmm2calibrate: kommandot finns inte
hmm2calibrate: komut yok
hmm2calibrate: nie znaleziono polecenia
hmm2calibrate: níor aimsíodh an t-ordú
hmm2calibrate: no se encontró la orden
hmm2calibrate: no s'ha trobat l'ordre
hmm2calibrate: opdracht niet gevonden
hmm2calibrate: parancs nem található
hmm2calibrate: perintah tidak ditemukan
hmm2calibrate: príkaz nenájdený
hmm2calibrate: příkaz nenalezen
hmm2calibrate: команда не найдена
hmm2calibrate: командата не е открита
hmm2calibrate: 命令找不到
hmm2calibrate: コマンドが見つかりません