designate: command not found

Have You tried accessing the binary with the full path?

Maybe Your $PATH variable doesn't contain the default paths? echo $PATH should give something like:

[root@server ~]# echo $PATH
/usr/local/sbin:/usr/local/bin:/sbin:/bin:/usr/sbin:/usr/bin:/root/bin

If it's empty, You may set the PATH variable with this command

export PATH="/usr/local/sbin:/usr/local/bin:/sbin:/bin:/usr/sbin:/usr/bin:/root/bin"

On Debian possible default full paths are:

/usr/bin/designate - from package: python-designateclient

You may install the required package with command apt-get install {package}
Error in other languages:
designate: bevel nie gevind nie
designate: comandă negăsită
designate: comando não encontrado
designate: commande introuvable
designate: command not found
designate: käsku ei ole
designate: không tìm thấy lệnh
designate: komanda nerasta
designate: Kommando nicht gefunden.
designate: kommandot finns inte
designate: komut yok
designate: nie znaleziono polecenia
designate: níor aimsíodh an t-ordú
designate: no se encontró la orden
designate: no s'ha trobat l'ordre
designate: opdracht niet gevonden
designate: parancs nem található
designate: perintah tidak ditemukan
designate: príkaz nenájdený
designate: příkaz nenalezen
designate: команда не найдена
designate: командата не е открита
designate: 命令找不到
designate: コマンドが見つかりません